Neuron. The structure of the nerve cell

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Neuron is the structural and functional unit of the nervous tissue. This is a specialized cell, which, along with general physiological properties (excitability, conductivity), also has a number of specific properties:

- Perceive information- translate the information of the stimulus into the biological language of the cell.

- Process information- i.e. carry out information analysis, synthesis - connection of various parts of information after analysis to obtain a new quality.

- encode information- convert information into a form convenient for storage in the brain.

- Form a team a control signal that spreads to other cells, neurons, muscle cells.

- Transfer of information neuron to other structures.

Neurons are able to communicate with other cells and have an informational impact on them (the place of contacts is the synapse).

All of its activities are carried out by the neuron count of 3 physiological properties (in addition to excitability and conductivity):

reception;

electrogenesis;

Neurosecretion.

AT general plan , all neurons have a body - a soma and processes - dendrites and axons.

They are conditionally divided by structure and functions into the following groups:

By body shape: polygonal, pyramidal, round, oval.

By the number and nature of the processes:

Unipolar- having one branch

Pseudounipolar- one process departs from the body, which then divides into 2 branches.

Bipolar- 2 processes, one dendritic, the other axon.

Multipolar- have 1 axon and many dendrites.

According to the mediator released by the neuron in the synapse: cholinergic, adrenergic, serotonergic, peptidergic, etc.

By function:

afferent, or sensitive - serve to perceive signals from the external and internal environment and transmit them to the central nervous system.

Insertion, or interneurons, intermediate - provide processing, storage and transmission of information to efferent neurons. Most of them are in the CNS.

Efferent or motor - form control signals, and transmit them to peripheral neurons and executive organs.

According to the physiological role: excitatory and inhibitory.

General neuron functions The central nervous system is the reception, coding, storage of information and the production of a neurotransmitter. Neurons, with the help of numerous synapses, receive signals in the form of postsynaptic potentials. Then they process this information and form a certain response. Consequently, they also perform an integrative, i.e. unifying function.

Communication between neurons, as can be seen, is carried out through the gap between the ends of the axon of one neuron and the dendrites of another. If they lie in sufficient proximity, i.e., the gap is small, then a synaptic node, or a synapse, connecting these two neurons, can form in this place.

Synapse similar to the resistance electrical circuit. If this resistance is high, then the connection between neurons is weak and the excitation of one neuron does not cause the excitation of another. If the “resistance” of the synapse is small, then there is a strong connection and the neuron is easily excited from the axon of another neuron connected to it.
The excitation of the neuron occurs according to the principle of "all or nothing". This means that a neuron can either be excited, and a nerve impulse goes from the cell along the axon to the synaptic nodes and then to other neurons, or it is not excited.

2. Humoral regulation. Functions, mechanisms of interaction of humoral substances with target cells. The place and role of the endocrine glands in the regulation of function.

Humoral regulation- one of the evolutionary early mechanisms of regulation of vital processes in the body, carried out through the liquid media of the body (blood, lymph, tissue fluid, oral cavity) with the help of hormones secreted by cells, organs, tissues. In highly developed animals, including humans, humoral regulation is subordinate to nervous regulation and, together with it, constitutes a single system of neurohumoral regulation. Metabolic products act not only directly on the effector organs, but also on the endings of sensory nerves (chemoreceptors) and nerve centers, causing certain reactions by humoral or reflex means. Humoral transmission of nerve impulses chemicals, mediators, is carried out in the central and peripheral nervous system. Along with hormones, products of intermediate metabolism play an important role in humoral regulation.

Biological activity liquid media the body is determined by the ratio of the content of catecholamines (adrenaline and norepinephrine, their precursors and decay products), acetylcholine, histamine, serotonin and other biogenic amines, some polypeptides and amino acids, the state of enzyme systems, the presence of activators and inhibitors, the content of ions, trace elements, etc.

Depending on the structure of the hormone, there are two types of interaction. If the hormone molecule lipophilic(for example, steroid hormones), then it can penetrate the lipid layer of the outer membrane of target cells. If the molecule is large or polar, then its penetration into the cell is impossible. Therefore, for lipophilic hormones, receptors are located inside target cells, and for hydrophilic The receptors are located in the outer membrane.

To get a cellular response the hormonal signal in the case of hydrophilic molecules is affected by an intracellular signal transduction mechanism. This happens with the participation of substances, which are called second intermediaries. Hormone molecules are very diverse in shape, but "second messengers" are not. The reliability of signal transmission provides a very high affinity of the hormone for its receptor protein.

Intermediaries- these are cyclic nucleotides (cAMP and cGMP), inositol triphosphate, calcium-binding protein - calmodulin, calcium ions, enzymes involved in the synthesis of cyclic nucleotides, as well as protein kinases - protein phosphorylation enzymes. All these substances are involved in the regulation of the activity of individual enzyme systems in target cells.

Exist two main ways of transmitting a signal to cells - targets from signaling molecules with a membrane mechanism of action: adenylate cyclase (or guanylate cyclase) systems; and phosphoinositide mechanism.

Cyclase system - it is a system consisting of adenosine cyclophosphate, adenylate cyclase and phosphodiesterase contained in the cell, which regulates the permeability of cell membranes, is involved in the regulation of many metabolic processes of a living cell, and mediates the action of certain hormones. That is, the role of the cyclase system is that they are the second mediators in the mechanism of action of hormones.

System "adenylate cyclase - cAMP". The membrane enzyme adenylate cyclase can be in two forms - activated and inactivated. Adenylate cyclase is activated under the influence of a hormone-receptor complex, the formation of which leads to the binding of guanyl nucleotide (GTP) to a specific regulatory stimulating protein (GS protein), after which the GS protein causes magnesium to attach to adenylate cyclase and activate it. This is how the hormones glucagon, thyrotropin, parathyrin, vasopressin, gonadotropin, etc., which activate adenylate cyclase, act. Some hormones, on the contrary, suppress adenylate cyclase (somatostatin, angiotensin-P, etc.)

Under the influence of adenylate cyclase cAMP is synthesized from ATP, causing the activation of protein kinases in the cytoplasm of the cell, which ensure the phosphorylation of numerous intracellular proteins. This changes the permeability of the membranes, i.e. causes metabolic and, accordingly, functional shifts typical for the hormone. The intracellular effects of cAMP are also manifested in the influence on the processes of proliferation, differentiation, and on the availability of membrane receptor proteins to hormone molecules.

Guanylate cyclase-cGMP system. Activation of membrane guanylate cyclase occurs not under the direct influence of the hormone-receptor complex, but indirectly through ionized calcium and oxidant systems of membranes. This is how atrial natriuretic hormone, an atriopeptide, a tissue hormone of the vascular wall, realizes its effects. In most tissues, the biochemical and physiological effects of cAMP and cGMP are opposite. Examples are the stimulation of heart contractions under the influence of cAMP and their inhibition by cGMP, the stimulation of contractions of intestinal smooth muscles by cGMP and the suppression of cAMP.

In addition to the adenylate cyclase or guanylate cyclase systems, there is also a mechanism for information transfer inside the target cell with the participation of calcium ions and inositol triphosphate.

Inositol triphosphate - this substance, which is a derivative of a complex lipid - inositol phosphatide. It is formed as a result of the action of a special enzyme - phospholipase "C", which is activated as a result of conformational changes in the intracellular domain of the membrane receptor protein. This enzyme hydrolyzes the phosphoester bond in the phosphatidyl-inositol-4,5-bisphosphate molecule, resulting in the formation of diacylglycerol and inositol triphosphate.

It is known that education diacylglycerol and inositol triphosphate leads to an increase in the concentration of ionized calcium inside the cell. This leads to the activation of many calcium-dependent proteins inside the cell, including the activation of various protein kinases. And here, as in the case of activation of the adenylate cyclase system, one of the stages of signal transmission inside the cell is protein phosphorylation, which leads to a physiological response of the cell to the action of the hormone.

In work phosphoinositide mechanism signaling in the target cell involves a special calcium-binding protein - calmodulin. This is a low molecular weight protein (17 kDa), 30% consisting of negatively charged amino acids (Glu, Asp) and therefore capable of actively binding Ca + 2. One calmodulin molecule has 4 calcium-binding sites. After interaction with Ca + 2, conformational changes in the calmodulin molecule occur and the Ca + 2-calmodulin complex becomes able to regulate the activity (allosterically inhibit or activate) many enzymes - adenylate cyclase, phosphodiesterase, Ca + 2, Mg + 2-ATPase and various protein kinases.

in different cells under the influence of the Ca + 2-calmodulin complex on isoenzymes of the same enzyme (for example, on adenylate cyclase of different types), in some cases, activation is observed, and in others, inhibition of the cAMP formation reaction. Such different effects occur because the allosteric centers of isoenzymes can include different amino acid radicals and their response to the action of the Ca + 2-calmodulin complex will be different.

Thus, in the role "second intermediaries" for signaling from hormones in target cells can be: cyclic nucleotides (c-AMP and c-GMP); Ca ions; complex "Sa-calmodulin"; diacylglycerol; inositol triphosphate.

The mechanisms for transmitting information from hormones inside target cells with the help of these mediators have common features : one of the steps in signal transduction is protein phosphorylation; termination of activation occurs as a result of special mechanisms initiated by the participants in the processes themselves - there are mechanisms of negative feedback.

Hormones are the main humoral regulators of the physiological functions of the body, and their properties, biosynthesis processes and mechanisms of action are now well known. Hormones are highly specific substances with respect to target cells and have a very high biological activity.

Endocrine glands - specialized organs that do not have excretory ducts and secrete into the blood, cerebral fluid, lymph through the intercellular gaps.

The physiological role of the endocrine glands associated with their influence on the mechanisms of regulation and integration, adaptation, maintaining the constancy of the internal environment of the body.

- (from the Greek neuron nerve) a nerve cell consisting of a body and processes extending from it with relatively short dendrites and a long axon; the main structural and functional unit of the nervous system (see diagram). Neurons conduct nerve impulses... Big Encyclopedic Dictionary

Afferent neuron- (sensitive, sensory) - a neuron that receives signals from receptors of the external and internal environment, transmits impulses to other neurons (associative, efferent) C.N.S ... Glossary of terms for the physiology of farm animals

BUT; m. [from Greek. neuron nerve] Spec. Nerve cell with all processes extending from it. * * * neuron (from the Greek néuron nerve), a nerve cell consisting of a body and processes extending from it with relatively short dendrites and a long axon; ... ... encyclopedic Dictionary

This term has other meanings, see Neuron (meanings). Not to be confused with neutron. Pyramidal neuron of the mouse cerebral cortex, expressive green fluorescent protein (GFP) Neuron (from ... Wikipedia

- (n. afferens, n. sensorium: synonym: N. receptor, N. sensory, N. sensitive) N., which perceives and transmits excitation from receptors to other N. of the central nervous system ... Big Medical Dictionary

- (sensitive neuron), a nerve cell that conducts information from RECEPTORS in any part of the body to the CENTRAL NERVOUS SYSTEM (CNS). Their nerve endings are located in the sense organs. see also MOTOR NEURON, NEURON, FEELINGS, NERVE ... Scientific and technical encyclopedic dictionary

A complex network of structures that permeates the entire body and ensures self-regulation of its vital activity due to the ability to respond to external and internal influences (stimuli). The main functions of the nervous system are receiving, storing and ... ... Collier Encyclopedia

Not to be confused with neutron. Pyramidal neuron cells in the mouse cerebral cortex A neuron (nerve cell) is a structural and functional unit of the nervous system. This cell has a complex structure, and is highly specialized in structure ... ... Wikipedia

Not to be confused with neutron. Pyramidal neuron cells in the mouse cerebral cortex A neuron (nerve cell) is a structural and functional unit of the nervous system. This cell has a complex structure, and is highly specialized in structure ... ... Wikipedia

This cell has a complex structure, is highly specialized and contains a nucleus, a cell body and processes in structure. There are over one hundred billion neurons in the human body.

Review

The complexity and diversity of the functions of the nervous system are determined by the interaction between neurons, which, in turn, are a set of different signals transmitted as part of the interaction of neurons with other neurons or muscles and glands. Signals are emitted and propagated by ions that generate electric charge, which moves along the neuron.

Structure

The neuron consists of a body with a diameter of 3 to 130 microns, containing a nucleus (with a large number of nuclear pores) and organelles (including a highly developed rough ER with active ribosomes, the Golgi apparatus), as well as processes. There are two types of processes: dendrites and. The neuron has a developed and complex cytoskeleton that penetrates into its processes. The cytoskeleton maintains the shape of the cell, its threads serve as "rails" for the transport of organelles and substances packed in membrane vesicles (for example, neurotransmitters). The cytoskeleton of a neuron consists of fibrils of different diameters: Microtubules (D = 20-30 nm) - consist of the protein tubulin and stretch from the neuron along the axon, up to the nerve endings. Neurofilaments (D = 10 nm) - together with microtubules provide intracellular transport of substances. Microfilaments (D = 5 nm) - consist of actin and myosin proteins, are especially pronounced in growing nerve processes and in. In the body of the neuron, a developed synthetic apparatus is revealed, the granular ER of the neuron stains basophilically and is known as the "tigroid". The tigroid penetrates into the initial sections of the dendrites, but is located at a noticeable distance from the beginning of the axon, which serves as a histological sign of the axon.

A distinction is made between anterograde (away from the body) and retrograde (towards the body) axon transport.

Dendrites and axon

An axon is usually a long process adapted to conduct from the body of a neuron. Dendrites are, as a rule, short and highly branched processes that serve as the main site for the formation of excitatory and inhibitory synapses that affect the neuron (different neurons have a different ratio of the length of the axon and dendrites). A neuron may have several dendrites and usually only one axon. One neuron can have connections with many (up to 20 thousand) other neurons.

Dendrites divide dichotomously, while axons give rise to collaterals. The branch nodes usually contain mitochondria.

Dendrites do not have a myelin sheath, but axons can. The place of generation of excitation in most neurons is the axon hillock - a formation at the place where the axon leaves the body. In all neurons, this zone is called the trigger zone.

Synapse(Greek σύναψις, from συνάπτειν - hug, embrace, shake hands) - the place of contact between two neurons or between a neuron and the effector cell receiving the signal. Serves for transmission between two cells, and during synaptic transmission, the amplitude and frequency of the signal can be regulated. Some synapses cause neuron depolarization, others hyperpolarization; the former are excitatory, the latter are inhibitory. Usually, to excite a neuron, stimulation from several excitatory synapses is necessary.

The term was introduced in 1897 by the English physiologist Charles Sherrington.

Classification

Structural classification

Based on the number and arrangement of dendrites and axons, neurons are divided into non-axonal, unipolar neurons, pseudo-unipolar neurons, bipolar neurons, and multipolar (many dendritic trunks, usually efferent) neurons.

Axonless neurons- small cells, grouped close in the intervertebral ganglia, having no anatomical signs of division of processes into dendrites and axons. All processes in a cell are very similar. The functional purpose of axonless neurons is poorly understood.

Unipolar neurons- neurons with one process, are present, for example, in the sensory nucleus of the trigeminal nerve in.

bipolar neurons- neurons with one axon and one dendrite, located in specialized sensory organs - the retina, olfactory epithelium and bulb, auditory and vestibular ganglia.

Multipolar neurons- Neurons with one axon and several dendrites. This type of nerve cells predominates in.

Pseudo-unipolar neurons- are unique in their kind. One process departs from the body, which immediately divides in a T-shape. This entire single tract is covered with a myelin sheath and structurally represents an axon, although along one of the branches, excitation goes not from, but to the body of the neuron. Structurally, dendrites are ramifications at the end of this (peripheral) process. The trigger zone is the beginning of this branching (that is, it is located outside the cell body). Such neurons are found in the spinal ganglia.

Functional classification

By position in the reflex arc, afferent neurons (sensitive neurons), efferent neurons (some of them are called motor neurons, sometimes this is not a very accurate name applies to the entire group of efferents) and interneurons (intercalary neurons) are distinguished.

Afferent neurons(sensitive, sensory or receptor). To neurons of this type include primary cells and pseudo-unipolar cells, in which dendrites have free endings.

Efferent neurons(effector, motor or motor). Neurons of this type include final neurons - ultimatum and penultimate - not ultimatum.

Associative neurons(intercalary or interneurons) - a group of neurons communicates between efferent and afferent, they are divided into intrusion, commissural and projection.

secretory neurons- neurons that secrete highly active substances (neurohormones). They have a well-developed Golgi complex, the axon ends in axovasal synapses.

Morphological classification

The morphological structure of neurons is diverse. In this regard, when classifying neurons, several principles are used:

  • take into account the size and shape of the body of the neuron;
  • the number and nature of branching processes;
  • the length of the neuron and the presence of specialized membranes.

According to the shape of the cell, neurons can be spherical, granular, stellate, pyramidal, pear-shaped, fusiform, irregular, etc. The size of the neuron body varies from 5 microns in small granular cells to 120-150 microns in giant pyramidal neurons. The length of a human neuron ranges from 150 microns to 120 cm.

According to the number of processes, the following morphological types of neurons are distinguished:

  • unipolar (with one process) neurocytes present, for example, in the sensory nucleus of the trigeminal nerve in;
  • pseudo-unipolar cells clustered nearby in the intervertebral ganglia;
  • bipolar neurons (have one axon and one dendrite) located in specialized sensory organs - the retina, olfactory epithelium and bulb, auditory and vestibular ganglia;
  • multipolar neurons (have one axon and several dendrites), predominant in the CNS.

Development and growth of a neuron

The neuron develops from a small progenitor cell that stops dividing even before it releases its processes. (However, the issue of neuronal division is currently debatable) As a rule, the axon begins to grow first, and dendrites form later. A thickening appears at the end of the developing process of the nerve cell irregular shape, which, apparently, paves the way through the surrounding tissue. This thickening is called the growth cone of the nerve cell. It consists of a flattened part of the process of the nerve cell with many thin spines. The microspinules are 0.1 to 0.2 µm thick and can be up to 50 µm in length; the wide and flat area of ​​the growth cone is about 5 µm wide and long, although its shape may vary. The spaces between the microspines of the growth cone are covered with a folded membrane. Microspines are in constant motion - some are drawn into the growth cone, others elongate, deviate in different directions, touch the substrate and can stick to it.

The growth cone is filled with small, sometimes interconnected, irregularly shaped membranous vesicles. Directly under the folded areas of the membrane and in the spines is a dense mass of entangled actin filaments. The growth cone also contains mitochondria, microtubules, and neurofilaments found in the body of the neuron.

Probably, microtubules and neurofilaments are elongated mainly due to the addition of newly synthesized subunits at the base of the neuron process. They move at a speed of about a millimeter per day, which corresponds to the speed of slow axon transport in a mature neuron. Since the average rate of advance of the growth cone is approximately the same, it is possible that neither assembly nor destruction of microtubules and neurofilaments occurs at the far end of the neuron process during the growth of the neuron process. New membrane material is added, apparently, at the end. The growth cone is an area of ​​rapid exocytosis and endocytosis, as evidenced by the many vesicles present here. Small membrane vesicles are transported along the process of the neuron from the cell body to the growth cone with a stream of fast axon transport. Membrane material is apparently synthesized in the body of the neuron, transported to the growth cone in the form of vesicles, and incorporated here into the plasma membrane by exocytosis, thus lengthening the outgrowth of the nerve cell.

The growth of axons and dendrites is usually preceded by a phase of neuronal migration, when immature neurons settle and find a permanent place for themselves.

1) central- dorsal and
2) peripheral- nerves and ganglions.

  • Nerves are bundles of nerve fibers surrounded by a connective tissue sheath.
  • Nerve nodes are clusters of neuron bodies outside the CNS, such as the solar plexus.

The nervous system is divided into two parts

1) somatic- controls skeletal muscles, obeys consciousness.
2) vegetative (autonomous)- manages internal organs, does not obey consciousness. Consists of two parts:

  • sympathetic: controls organs during times of stress and exercise
    • increases heart rate, blood pressure and blood glucose levels
    • activates the nervous system and sensory organs
    • dilates the bronchi and pupil
    • slows down the digestive system.
  • parasympathetic the system works at rest, brings the work of the organs back to normal (opposite functions).

reflex arc

This is the path along which the nerve impulse passes during implementation. Consists of 5 parts
1) Receptor- a sensitive formation capable of responding to a certain type of stimulus; converts irritation into a nerve impulse.
2) By sensitive neuron the nerve impulse goes from the receptor to the central nervous system (spinal cord or brain).
3) Interneuron located in the brain, transmits a signal from a sensitive neuron to an executive one.
4) By executive (motor) neuron nerve impulse goes from the brain to the working organ.
5) Working (executive) body- muscle (contracts), gland (secrets), etc.

Analyzer

This is a system of neurons that perceive irritation, conduct nerve impulses and provide information processing. Consists of 3 departments:
1) peripheral- these are receptors, for example, cones and rods in the retina of the eye
2) conductive are the nerves and pathways of the brain
3) central located in the cortex - here the final analysis of information takes place.

Choose the one most correct option. The department of the auditory analyzer, which transmits nerve impulses to the human brain, is formed
1) auditory nerves
2) receptors located in the cochlea
3) eardrum
4) auditory ossicles

Answer


Choose three correct answers from six and write down the numbers under which they are indicated. What examples illustrate the excitation of the sympathetic nervous system?
1) increased heart rate
2) increased intestinal motility
3) lowering blood pressure
4) dilation of the pupils of the eyes
5) increase in blood sugar
6) narrowing of the bronchi and bronchioles

Answer


Choose three correct answers from six and write down the numbers under which they are indicated. What effect does the parasympathetic nervous system have on the human body?
1) increases the heart rate
2) activates salivation
3) stimulates the production of adrenaline
4) enhances the formation of bile
5) increases intestinal peristalsis
6) mobilizes the functions of organs under stress

Answer


Choose one, the most correct option. Nerve impulses from receptors to the central nervous system conduct
1) sensitive neurons
2) motor neurons
3) sensory and motor neurons
4) intercalary and motor neurons

Answer


Choose three correct answers from six and write down the numbers under which they are indicated. Receptors are nerve endings in the human body that
1) perceive information from the external environment
2) perceive impulses from the internal environment
3) perceive excitation transmitted to them through motor neurons
4) are located in the executive body
5) convert perceived stimuli into nerve impulses
6) realize the body's response to irritation from the external and internal environment

Answer


Choose one, the most correct option. Peripheral part of the visual analyzer
1) optic nerve
2) visual receptors
3) pupil and lens
4) visual cortex

Answer


Choose one, the most correct option. Reflexes that cannot be enhanced or inhibited by the will of a person are carried out through the nervous system
1) central
2) vegetative
3) somatic
4) peripheral

Answer


1. Establish a correspondence between the feature of regulation and the department of the nervous system that implements it: 1) somatic, 2) vegetative
A) regulates the work of skeletal muscles
B) regulates metabolic processes
B) provides voluntary movements
D) is carried out autonomously, regardless of the desire of a person
D) controls the activity of smooth muscles

Answer


2. Establish a correspondence between the function of the human peripheral nervous system and the department that performs this function: 1) somatic, 2) vegetative
A) directs commands to skeletal muscles
B) innervates the smooth muscles of the internal organs
B) provides movement of the body in space
D) regulates the work of the heart
D) enhances the work of the digestive glands

Answer


3. Establish a correspondence between the characteristics and the department of the human nervous system: 1) somatic, 2) vegetative. Write down the numbers 1 and 2 in the order corresponding to the letters.
A) directs commands to skeletal muscles
B) changes the activity of various glands
C) forms only a three-neuron reflex arc
D) changes the heart rate
D) causes voluntary body movements
E) regulates smooth muscle contraction

Answer


4. Establish a correspondence between the properties of the nervous system and its types: 1) somatic, 2) vegetative. Write down the numbers 1 and 2 in right order.
A) innervates the skin and skeletal muscles
B) innervates all internal organs
C) actions are not subject to consciousness (autonomous)
D) actions are controlled by consciousness (arbitrary)
D) helps to maintain the connection of the body with the external environment
E) regulates metabolic processes, body growth

Answer


5. Establish a correspondence between the types of the nervous system and their characteristics: 1) vegetative, 2) somatic. Write down the numbers 1 and 2 in the order corresponding to the letters.
A) regulates the work of internal organs
B) regulates the work of skeletal muscles
C) reflexes are carried out quickly and obey the human mind
D) reflexes are slow and do not obey human consciousness
D) the highest organ of this system is the hypothalamus
E) the highest center of this system is the cerebral cortex

Answer


6n. Establish a correspondence between the characteristic and the department of the human nervous system to which it belongs: 1) somatic, 2) vegetative. Write down the numbers 1 and 2 in the order corresponding to the letters.
A) regulates the diameter of blood vessels
B) has a reflex arc motor pathway, consisting of two neurons
B) provides a variety of body movements
D) works arbitrarily
D) supports the activity of internal organs

Answer


Establish a correspondence between the organs and types of the nervous system that control their activity: 1) somatic, 2) vegetative. Write the numbers 1 and 2 in the correct order.
A) bladder
B) liver
B) biceps
D) intercostal muscles
D) intestines
E) oculomotor muscles

Answer


Choose three options. Hearing analyzer includes
1) auditory ossicles
2) receptor cells
3) auditory tube
4) sensory nerve
5) semicircular canals
6) cortex of the temporal lobe

Answer


Choose one, the most correct option. Nerve impulses are transmitted to the brain through neurons
1) motor
2) insert
3) sensitive
4) executive

Answer


Choose three consequences of irritation of the sympathetic department of the central nervous system:
1) increased and increased heart contractions
2) slowing down and weakening of heart contractions
3) slowing down the formation of gastric juice
4) increased intensity of activity of the stomach glands
5) weakening of the wave-like contractions of the intestinal walls
6) strengthening of undulating contractions of the intestinal walls

Answer


1. Establish a correspondence between the function of organs and the department of the autonomic nervous system that performs it: 1) sympathetic, 2) parasympathetic
A) increased secretion of digestive juices
B) slow heart rate
B) increased ventilation of the lungs
D) pupil dilation
D) increased undulating bowel movements

Answer


2. Establish a correspondence between the function of organs and the department of the autonomic nervous system that performs it: 1) sympathetic, 2) parasympathetic
A) raises the heart rate
B) reduces the frequency of breathing
C) stimulates the secretion of digestive juices
D) stimulates the release of adrenaline into the blood
D) increases ventilation of the lungs

Answer


3. Establish a correspondence between the function of the autonomic nervous system and its department: 1) sympathetic, 2) parasympathetic
A) raises blood pressure
B) enhances the separation of digestive juices
B) lowers the heart rate
D) reduces intestinal peristalsis
D) increases blood flow in the muscles

Answer


4. Establish a correspondence between the functions and divisions of the autonomic nervous system: 1) sympathetic, 2) parasympathetic. Write down the numbers 1 and 2 in the order corresponding to the letters.
A) dilates the arteries
B) speeds up the heartbeat
C) enhances intestinal peristalsis and stimulates the digestive glands
D) constricts the bronchi and bronchioles, reduces ventilation of the lungs
D) dilated pupils

Answer


Choose one, the most correct option. What are nerves made up of?
1) an accumulation of nerve cells in the brain
2) clusters of nerve cells outside the central nervous system
3) nerve fibers with a connective tissue sheath
4) white matter located in the central nervous system

Answer


Choose three anatomical structures that are the initial link of human analyzers
1) eyelids with eyelashes
2) rods and cones of the retina
3) auricle
4) cells of the vestibular apparatus
5) lens of the eye
6) taste buds of the tongue

Answer


Choose one, the most correct option. A system of neurons that perceive stimuli, conduct nerve impulses and provide information processing is called
1) nerve fiber

3) nerve
4) analyzer

Answer


Choose one, the most correct option. What is the name of the system of neurons that perceive stimuli, conduct nerve impulses and provide information processing
1) nerve fiber
2) central nervous system
3) nerve
4) analyzer

Answer


Choose three options. The visual analyzer includes
1) the white of the eye
2) retinal receptors
3) vitreous body
4) sensory nerve
5) cortex of the occipital lobe
6) lens

Answer


Choose one, the most correct option. The peripheral part of the human auditory analyzer is formed by
1) ear canal and eardrum
2) bones of the middle ear
3) auditory nerves
4) sensitive snail cells

Answer


With excitation of the sympathetic nervous system, in contrast to excitation of the parasympathetic nervous system
1) arteries dilate
2) blood pressure rises
3) intestinal motility increases
4) the pupil narrows
5) increases the amount of sugar in the blood
6) heart contractions become more frequent

Answer


1. Set the sequence of parts of the reflex arc when a nerve impulse passes through it. Write down the corresponding sequence of numbers.
1) sensitive neuron
2) working body
3) intercalary neuron
4) department of the cerebral cortex
5) receptor
6) motor neuron

Answer


2. Establish the sequence of links in the reflex arc of the sweating reflex. Write down the corresponding sequence of numbers.
1) occurrence in the receptors of nerve impulses
2) sweating
3) excitation of motor neurons
4) irritation of skin receptors that perceive heat
5) transmission of nerve impulses to the sweat glands
6) transmission of nerve impulses along sensory neurons in the central nervous system

Answer


3. Establish the sequence of nerve impulse conduction in the reflex arc, which provides one of the mechanisms of thermoregulation in the human body. Write down the corresponding sequence of numbers.
1) transmission of a nerve impulse along a sensitive neuron to the central nervous system
2) transmission of a nerve impulse to motor neurons
3) excitation of skin thermoreceptors with a decrease in temperature
4) transmission of a nerve impulse to intercalary neurons
5) decrease in the lumen of the blood vessels of the skin

Answer


Choose three options. Interneurons in the human nervous system transmit nerve impulses
1) from a motor neuron to the brain
2) from the working body to the spinal cord
3) from the spinal cord to the brain
4) from sensitive neurons to working organs
5) from sensory neurons to motor neurons
6) from the brain to motor neurons

Answer


Arrange in the correct order the elements of the human knee reflex reflex arc. Write down the numbers in the answer in the order corresponding to the letters.
1) Motor neuron
2) Sensitive neuron
3) Back brain
4) Tendon receptors
5) Quadriceps femoris

Answer


Choose three functions of the sympathetic nervous system. Write down the numbers under which they are indicated.
1) enhances ventilation of the lungs
2) reduces heart rate
3) lowers blood pressure
4) inhibits the secretion of digestive juices
5) enhances intestinal motility
6) dilates pupils

Answer


Choose one, the most correct option. Sensory neurons in the three-neuron reflex arc are connected to
1) processes of intercalary neurons
2) bodies of intercalary neurons
3) motor neurons
4) executive neurons

Answer


Establish a correspondence between the functions and types of neurons: 1) sensitive, 2) intercalary, 3) motor. Write down the numbers 1, 2, 3 in the order corresponding to the letters.
A) transmission of nerve impulses from the sense organs to the brain
B) transmission of nerve impulses from internal organs to the brain
B) transmission of nerve impulses to muscles
D) transmission of nerve impulses to the glands
D) transmission of nerve impulses from one neuron to another

Answer


Choose three correct answers from six and write down the numbers under which they are indicated. What organs are controlled by the autonomic nervous system?
1) organs of the digestive tract
2) gonads
3) limb muscles
4) heart and blood vessels
5) intercostal muscles
6) chewing muscles

Answer


Choose three correct answers from six and write down the numbers under which they are indicated. The central nervous system is
1) sensory nerves
2) spinal cord
3) motor nerves
4) cerebellum
5) bridge
6) nerve nodes

Answer


Analyze the Neurons table. For each cell labeled with a letter, select the appropriate term from the list provided. © D.V. Pozdnyakov, 2009-2019

, complex network structures, penetrating the entire body and providing self-regulation of its vital activity due to the ability to respond to external and internal influences (stimuli). The main functions of the nervous system are the receipt, storage and processing of information from the external and internal environment, the regulation and coordination of the activities of all organs and organ systems. In humans, as in all mammals, the nervous system includes three main components: 1) nerve cells (neurons); 2) glial cells associated with them, in particular neuroglial cells, as well as cells that form neurilemma; 3) connective tissue. Neurons provide the conduction of nerve impulses; neuroglia performs supporting, protective and trophic functions both in the brain and spinal cord, and neurilemma, which consists mainly of specialized, so-called. Schwann cells, participates in the formation of sheaths of peripheral nerve fibers; connective tissue supports and links together the various parts of the nervous system.

The human nervous system is divided in different ways. Anatomically, it consists of the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS includes the brain and spinal cord, and the PNS, which provides communication between the CNS and various parts body - cranial and spinal nerves, as well as nerve nodes (ganglia) and nerve plexuses that lie outside the spinal cord and brain.

Neuron. The structural and functional unit of the nervous system is a nerve cell - a neuron. It is estimated that there are more than 100 billion neurons in the human nervous system. A typical neuron consists of a body (i.e., a nuclear part) and processes, one usually non-branching process, an axon, and several branching ones, dendrites. The axon carries impulses from the cell body to the muscles, glands, or other neurons, while the dendrites carry them to the cell body.

In a neuron, as in other cells, there is a nucleus and a number of tiny structures - organelles.

(see also CELL). These include the endoplasmic reticulum, ribosomes, Nissl bodies (tigroid), mitochondria, the Golgi complex, lysosomes, filaments (neurofilaments and microtubules).Nerve impulse. If the stimulation of a neuron exceeds a certain threshold value, then a series of chemical and electrical changes occur at the point of stimulation, which spread throughout the neuron. Transmitted electrical changes are called nerve impulses. Unlike a simple electric discharge, which, due to the resistance of the neuron, will gradually weaken and be able to overcome only a short distance, a much slower “running” nerve impulse is constantly restored (regenerates) in the process of propagation.

The concentrations of ions (electrically charged atoms) - mainly sodium and potassium, as well as organic substances - outside the neuron and inside it are not the same, so the nerve cell at rest is negatively charged from the inside, and positively from the outside; as a result, a potential difference appears on the cell membrane (the so-called "resting potential" is approximately -70 millivolts). Any change that reduces the negative charge inside the cell and thereby the potential difference across the membrane is called depolarization.

The plasma membrane surrounding a neuron is a complex formation consisting of lipids (fats), proteins and carbohydrates. It is practically impermeable to ions. But some of the protein molecules in the membrane form channels through which certain ions can pass. However, these channels, called ionic channels, are not always open, but, like gates, they can open and close.

When a neuron is stimulated, some of the sodium (Na

+ ) channels open at the point of stimulation, due to which sodium ions enter the cell. The influx of these positively charged ions reduces the negative charge of the inner surface of the membrane in the region of the channel, which leads to depolarization, which is accompanied by a sharp change in voltage and a discharge - a so-called. "action potential", i.e. nerve impulse. The sodium channels then close.

In many neurons, depolarization also causes the opening of potassium (

K+ ) channels, as a result of which potassium ions leave the cell. The loss of these positively charged ions again increases the negative charge on the inner surface of the membrane. The potassium channels then close. Other membrane proteins also begin to work - the so-called. potassium-sodium pumps that move Na+ from the cell, and K + inside the cell, which, along with the activity of potassium channels, restores the initial electrochemical state (resting potential) at the point of stimulation.

Electrochemical changes at the point of stimulation cause depolarization at the adjacent point of the membrane, triggering the same cycle of changes in it. This process is constantly repeated, and at each new point where depolarization occurs, an impulse of the same magnitude is born as at the previous point. Thus, together with the renewed electrochemical cycle, the nerve impulse propagates along the neuron from point to point.

Nerves, nerve fibers and ganglia. A nerve is a bundle of fibers, each of which functions independently of the others. The fibers in a nerve are organized into groups surrounded by specialized connective tissue, in which the vessels supplying the nerve fibers run. nutrients and oxygen and removing carbon dioxide and decay products. Nerve fibers along which impulses propagate from peripheral receptors to the central nervous system (afferent) are called sensitive or sensory. Fibers that transmit impulses from the central nervous system to muscles or glands (efferent) are called motor or motor. Most nerves are mixed and consist of both sensory and motor fibers. A ganglion (ganglion) is a cluster of neuron bodies in the peripheral nervous system.

Axon fibers in the PNS are surrounded by a neurilemma - a sheath of Schwann cells that are located along the axon, like beads on a thread. A significant number of these axons are covered with an additional sheath of myelin (a protein-lipid complex); they are called myelinated (meaty). Fibers that are surrounded by neurilemma cells, but not covered with a myelin sheath, are called unmyelinated (non-myelinated). Myelinated fibers are found only in vertebrates. The myelin sheath is formed from the plasma membrane of the Schwann cells, which winds around the axon like a roll of ribbon, forming layer upon layer. The area of ​​the axon where two adjacent Schwann cells touch each other is called the node of Ranvier. In the CNS, the myelin sheath of nerve fibers is formed by a special type of glial cells - oligodendroglia. Each of these cells forms the myelin sheath of several axons at once. Unmyelinated fibers in the CNS lack a sheath of any special cells.

The myelin sheath accelerates the conduction of nerve impulses that "jump" from one node of Ranvier to another, using this sheath as a connecting electrical cable. The speed of impulse conduction increases with the thickening of the myelin sheath and ranges from 2 m / s (along unmyelinated fibers) to 120 m / s (along fibers, especially rich in myelin). For comparison: the propagation speed electric current on metal wires - from 300 to 3000 km / s.

Synapse. Each neuron has a specialized connection to muscles, glands, or other neurons. The zone of functional contact between two neurons is called a synapse. Interneuronal synapses are formed between different parts of two nerve cells: between an axon and a dendrite, between an axon and a cell body, between a dendrite and a dendrite, between an axon and an axon. A neuron that sends an impulse to a synapse is called presynaptic; the neuron receiving the impulse is postsynaptic. The synaptic space is slit-shaped. A nerve impulse propagating along the membrane of a presynaptic neuron reaches the synapse and stimulates the release of a special substance - a neurotransmitter - into a narrow synaptic cleft. Neurotransmitter molecules diffuse through the cleft and bind to receptors on the membrane of the postsynaptic neuron. If the neurotransmitter stimulates the postsynaptic neuron, its action is called excitatory; if it suppresses, it is called inhibitory. The result of the summation of hundreds and thousands of excitatory and inhibitory impulses simultaneously flowing to a neuron is the main factor determining whether this postsynaptic neuron will generate a nerve impulse at a given moment.

In a number of animals (for example, in the spiny lobster), a particularly close connection is established between the neurons of certain nerves with the formation of either an unusually narrow synapse, the so-called. gap junction, or, if neurons are in direct contact with each other, tight junction. Nerve impulses pass through these connections not with the participation of a neurotransmitter, but directly, by electrical transmission. A few dense junctions of neurons are also found in mammals, including humans.

Regeneration. By the time a person is born, all his neurons and bMost of the interneuronal connections have already been formed, and in the future only single new neurons are formed. When a neuron dies, it is not replaced by a new one. However, the remaining ones can take over the functions of the lost cell, forming new processes that form synapses with those neurons, muscles or glands with which the lost neuron was connected.

Cut or damaged PNS neuron fibers surrounded by neurilemma can regenerate if the cell body remains intact. Below the site of transection, the neurilemma is preserved as a tubular structure, and that part of the axon that remains connected with the cell body grows along this tube until it reaches the nerve ending. Thus, the function of the damaged neuron is restored. Axons in the CNS that are not surrounded by a neurilemma are apparently unable to grow back to the site of their former termination. However, many CNS neurons can give rise to new short processes - branches of axons and dendrites that form new synapses.

CENTRAL NERVOUS SYSTEM The CNS consists of the brain and spinal cord and their protective membranes. The outermost is the dura mater, under it is the arachnoid (arachnoid), and then the pia mater, fused with the surface of the brain. Between the soft and arachnoid membranes is the subarachnoid (subarachnoid) space containing the cerebrospinal (cerebrospinal) fluid, in which both the brain and the spinal cord literally float. The action of the buoyancy force of the liquid leads to the fact that, for example, the brain of an adult, having an average mass of 1500 g, actually weighs 50-10 g inside the skull. 0 d. The meninges and cerebrospinal fluid also act as shock absorbers, softening all kinds of shocks and shocks that the body experiences and which could lead to damage to the nervous system.

The CNS is made up of gray and white matter. Gray matter is made up of cell bodies, dendrites, and unmyelinated axons, organized into complexes that include countless synapses and serve as information processing centers for many of the functions of the nervous system. White matter consists of myelinated and unmyelinated axons, which act as conductors that transmit impulses from one center to another. The composition of gray and white matter also includes glial cells.

CNS neurons form many circuits that perform two main functions: they provide reflex activity, as well as complex information processing in higher brain centers. These higher centers, such as the visual cortex (visual cortex), receive incoming information, process it, and transmit a response signal along the axons.

The result of the activity of the nervous system is one or another activity, which is based on the contraction or relaxation of muscles or the secretion or cessation of secretion of glands. It is with the work of muscles and glands that any way of our self-expression is connected.

Incoming sensory information is processed by passing through a sequence of centers connected by long axons, which form specific pathways, such as pain, visual, auditory. Sensitive (ascending) pathways go in an ascending direction to the centers of the brain. Motor (descending) pathways connect the brain with the motor neurons of the cranial and spinal nerves.

Pathways are usually organized in such a way that information (for example, pain or tactile) from the right side of the body goes to the left side of the brain and vice versa. This rule also applies to descending motor pathways: the right half of the brain controls the movements of the left half of the body, and the left half controls the right. There are a few exceptions to this general rule, however.

Brain consists of three main structures: the cerebral hemispheres, the cerebellum and the trunk.

The cerebral hemispheres - the largest part of the brain - contain higher nerve centers that form the basis of consciousness, intellect, personality, speech, and understanding. In each of the large hemispheres, the following formations are distinguished: isolated accumulations (nuclei) of gray matter lying in the depths, which contain many important centers; a large array of white matter located above them; covering the hemispheres from the outside, a thick layer of gray matter with numerous convolutions, constituting the cerebral cortex.

The cerebellum also consists of a deep gray matter, an intermediate array of white matter, and an outer thick layer of gray matter that forms many convolutions. The cerebellum provides mainly coordination of movements.

The brain stem is formed by a mass of gray and white matter, not divided into layers. The trunk is closely connected with the cerebral hemispheres, cerebellum and spinal cord and contains numerous centers of sensory and motor pathways. The first two pairs of cranial nerves depart from the cerebral hemispheres, the remaining ten pairs from the trunk. The trunk regulates such vital functions as breathing and blood circulation.

see also THE HUMAN BRAIN.Spinal cord . Located inside the spinal column and protected by its bone tissue, the spinal cord has cylindrical shape and covered with three shells. On a transverse section, the gray matter has the shape of the letter H or a butterfly. Gray matter is surrounded by white matter. The sensory fibers of the spinal nerves end in the dorsal (posterior) sections of the gray matter - the posterior horns (at the ends of H facing the back). The bodies of motor neurons of the spinal nerves are located in the ventral (anterior) sections of the gray matter - the anterior horns (at the ends of H, remote from the back). In the white matter, there are ascending sensory pathways ending in the gray matter of the spinal cord, and descending motor pathways coming from the gray matter. In addition, many fibers in the white matter connect the different parts of the gray matter of the spinal cord. PERIPHERAL NERVOUS SYSTEM The PNS provides a two-way connection between the central parts of the nervous system and the organs and systems of the body. Anatomically, the PNS is represented by cranial (cranial) and spinal nerves, as well as a relatively autonomous enteric nervous system localized in the intestinal wall.

All cranial nerves (12 pairs) are divided into motor, sensory or mixed. The motor nerves originate in the motor nuclei of the trunk, formed by the bodies of the motor neurons themselves, and the sensory nerves are formed from the fibers of those neurons whose bodies lie in the ganglia outside the brain.

31 pairs of spinal nerves depart from the spinal cord: 8 pairs of cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal. They are designated in accordance with the position of the vertebrae adjacent to the intervertebral foramina, from which these nerves exit. Each spinal nerve has anterior and posterior roots, which fuse to form the nerve itself. The back root contains sensory fibers; it is closely related to the spinal ganglion (posterior root ganglion), which consists of the bodies of neurons whose axons form these fibers. The anterior root consists of motor fibers formed by neurons whose cell bodies lie in the spinal cord.

cranial nerves

Name

Functional characteristic

Innervated structures

Olfactory Special sensory (smell) Olfactory epithelium of the nasal cavity
Visual Special touch(vision) Rods and cones of the retina
Oculomotor Motor Most of the external muscles of the eye
Smooth muscles of the iris and lens
Blocky Motor Superior oblique muscle of the eye
ternary All-sensory
Motor
Skin of the face, mucous membrane of the nose and mouth
Chewing muscles
diverting Motor External rectus eye
Facial Motor
visceromotor
Special touch
Mimic muscles
Salivary glands
Taste buds of the tongue
vestibulocochlear Special touch
Vestibular (balance) Auditory (hearing)
Semicircular canals and spots (receptor sites) of the labyrinth
Auditory organ in the cochlea (inner ear)
Glossopharyngeal Motor
visceromotor
Viscerosensory
Muscles of the posterior wall of the pharynx
Salivary glands
Receptors for taste and general sensitivity in the back
parts of the mouth
Wandering Motor
visceromotor

Viscerosensory

All-sensory

Muscles of the larynx and pharynx
heart muscle, smooth muscle, lung glands,
bronchi, stomach and intestines, including digestive glands
Receptors in large blood vessels, lungs, esophagus, stomach, and intestines
outer ear
Additional Motor Sternocleidomastoid and trapezius muscles
Sublingual Motor Muscles of the tongue
The definitions "visceromotor", "viscerosensory" indicate the connection of the corresponding nerve with the internal (visceral) organs.
AUTONOMIC SYSTEM The autonomic, or autonomic, nervous system regulates the activity of the involuntary muscles, the heart muscle, and various glands. Its structures are located both in the central nervous system and in the peripheral. The activity of the autonomic nervous system is aimed at maintaining homeostasis, i.e. a relatively stable state of the internal environment of the body, such as a constant body temperature or blood pressure corresponding to the needs of the body.

Signals from the CNS arrive at the working (effector) organs through pairs of series-connected neurons. The bodies of neurons of the first level are located in the CNS, and their axons terminate in the autonomic ganglia lying outside the CNS, and here they form synapses with the bodies of neurons of the second level, the axons of which directly contact the effector organs. The first neurons are called preganglionic, the second - postganglionic.

In that part of the autonomic nervous system, which is called the sympathetic, the bodies of preganglionic neurons are located in the gray matter of the thoracic (thoracic) and lumbar (lumbar) spinal cord. Therefore, the sympathetic system is also called the thoraco-lumbar system. The axons of its preganglionic neurons terminate and form synapses with postganglionic neurons in the ganglia located in a chain along the spine. Axons of postganglionic neurons are in contact with effector organs. The endings of postganglionic fibers secrete norepinephrine (a substance close to adrenaline) as a neurotransmitter, and therefore the sympathetic system is also defined as adrenergic.

The sympathetic system is complemented by the parasympathetic nervous system. The bodies of its pregangliar neurons are located in the brainstem (intracranial, i.e. inside the skull) and the sacral (sacral) section of the spinal cord. Therefore, the parasympathetic system is also called the craniosacral system. Axons of preganglionic parasympathetic neurons terminate and form synapses with postganglionic neurons in the ganglia located near the working organs. The endings of postganglionic parasympathetic fibers release the neurotransmitter acetylcholine, on the basis of which the parasympathetic system is also called the cholinergic system.

As a rule, the sympathetic system stimulates those processes that are aimed at mobilizing the body's forces in extreme situations or under stress. The parasympathetic system contributes to the accumulation or restoration of the body's energy resources.

The reactions of the sympathetic system are accompanied by the consumption of energy resources, an increase in the frequency and strength of heart contractions, an increase in blood pressure and blood sugar, as well as an increase in blood flow to skeletal muscles due to a decrease in its flow to internal organs and skin. All of these changes are characteristic of the "fright, flight or fight" response. The parasympathetic system, on the contrary, reduces the frequency and strength of heart contractions, lowers blood pressure, and stimulates the digestive system.

The sympathetic and parasympathetic systems act in a coordinated manner and cannot be regarded as antagonistic. Together they support the functioning of internal organs and tissues at a level corresponding to the intensity of stress and emotional state person. Both systems function continuously, but their activity levels fluctuate depending on the situation.

REFLEXES When an adequate stimulus acts on the receptor of a sensory neuron, a volley of impulses arises in it, triggering a response action, called a reflex act (reflex). Reflexes underlie most of the manifestations of the vital activity of our body. The reflex act is carried out by the so-called. reflex arc; this term refers to the path of transmission of nerve impulses from the point of initial stimulation on the body to the organ that performs the response.

The arc of the reflex that causes contraction of the skeletal muscle consists of at least two neurons: a sensory one, whose body is located in the ganglion, and the axon forms a synapse with the neurons of the spinal cord or brain stem, and the motor (lower, or peripheral, motor neuron), whose body is located in gray matter, and the axon terminates in a motor end plate on skeletal muscle fibers.

The reflex arc between the sensory and motor neurons can also include a third, intermediate, neuron located in the gray matter. The arcs of many reflexes contain two or more intermediate neurons.

Reflex actions are carried out involuntarily, many of them are not realized. The knee jerk, for example, is elicited by tapping the quadriceps tendon at the knee. This is a two-neuron reflex, its reflex arc consists of muscle spindles (muscle receptors), a sensory neuron, a peripheral motor neuron, and a muscle. Another example is the reflex withdrawal of a hand from a hot object: the arc of this reflex includes a sensory neuron, one or more intermediate neurons in the gray matter of the spinal cord, a peripheral motor neuron, and a muscle.

Many reflex acts are much more complex mechanism. The so-called intersegmental reflexes are made up of combinations of simpler reflexes, in the implementation of which many segments of the spinal cord take part. Thanks to such reflexes, for example, coordination of the movements of the arms and legs when walking is ensured. The complex reflexes that close in the brain include movements associated with maintaining balance. Visceral reflexes, i.e. reflex reactions of internal organs mediated by the autonomic nervous system; they provide emptying of the bladder and many processes in the digestive system.

see also REFLEX. DISEASES OF THE NERVOUS SYSTEM Damage to the nervous system occurs with organic diseases or injuries of the brain and spinal cord, meninges, peripheral nerves. Diagnosis and treatment of diseases and injuries of the nervous system is the subject of a special branch of medicine - neurology. Psychiatry and clinical psychology deal mainly with mental disorders. The areas of these medical disciplines often overlap.See individual diseases of the nervous system : ALZHEIMER'S DISEASE; STROKE; MENINGITIS; NEURITIS; PARALYSIS; PARKINSON'S DISEASE; POLIO; MULTIPLE SCLEROSIS; TETANUS; CEREBRAL PALSY; CHOREA; ENCEPHALITIS; EPILEPSY. see also ANATOMY COMPARATIVE; HUMAN ANATOMY. LITERATURE Bloom F., Leizerson A., Hofstadter L.Brain, mind and behavior . M., 1988
human physiology , ed. R. Schmidt, G. Tevsa, vol. 1. M., 1996

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